Delayed union of femoral fractures in older rats:decreased gene expression

Delayed union of femoral fractures in older rats:decreased gene expression

BACKGROUND Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26 weeks. The possible role of altered mRNA gene expression in this delayed union was studied. Closed mid-shaft femoral fractures were induced followed by euthanasia at 0 time (unfractured) or at 1, 2, 4 or 6 weeks after fracture in 6-w...

Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures.

INTRODUCTION Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process and prognosis. This study aims to describe the epidemiology and health outcomes of femoral and tibial shaft fractures treated at two level I trauma centres, by comparing the differences between patients with delayed union...

Nutritionally Induced Delayed Union Model of Femur Fractures in Mice

Exchange nailing for non-union of femoral shaft fractures.

BACKGROUND There are many ways to treat aseptic non-union of femoral shaft fractures with reported varied success rate. Amongst all these, Exchange nailing is the simplest and most successful technique for treating aseptic non union of femoral shaft fractures. We have carried out a prospective study in the Department of Trauma & Orthopaedics, Ayub Medical College Abbottabad to analyse the role ...

Delayed union stress fractures of the anterior tibia: conservative management.

INTRODUCTION A conservative method of treating four delayed union stress fractures of the anterior mid-tibia is described, with an illustrative case history. METHODS Once diagnosed each of the patients was treated in a pneumatic lower leg brace with modified rest. The mean (range) age of the patients was 28 (24-32) years and all were involved in professional or amateur sports. The mean (range...